The South African was surprisingly beaten by Brazilian Alan Fonteles Cardoso Oliveira over 200m on Saturday but showed he is still a force to be reckoned with to move through to tomorrow's final.
Pistorius clocked 11.18 to finish 0.16 ahead of the USA's Blake Leeper.
He will be joined in the showpiece by British teenager Jonnie Peacock, who came home in the first heat in 11.08 seconds, equalling the T44 Paralympic record.
It was a baptism of fire for Peacock, who beat the USA's world champion Jerome Singleton and Brazilian Alan.
Singleton finished second to also make it through while the times in the second two heats ensured that Alan too made it through as a fastest loser, setting up a mouthwatering final tomorrow night which looks too close to call.