The world champions and gold medal favourites got the men's tournament off to a flying start, putting on a dominant display to beat Great Britain 11-1.
The match's top scorer Genrik Pavliukianec scored an impressive four goals and gave the hosts plenty to think about.
'Facing Lithuania was always going to be hard,' said ParalympicsGB's Niall Graham.
'We've something to build on and we can only come back stronger.'
In the second of this morning's three Group A matches, Brazil held off a resurgent Finland to win a closely-fought match 6-5. Trailing 5-1 with time running out, Finland scored four goals in just two minutes before finally succumbing to a sixth Brazilian goal.
'It was a very exciting game but we won with the 'forza dos seis' - the force of the six,' said Brazil's Filippe Santos Silvestre.
'Even though there are only three of us out there (on the court), we have six in the squad and the three on the bench played really well.'
There are six Goalball players in a team, but only three are allowed on court at any one time.
In the morning's third and final Group A match, Turkey beat Sweden 9-2.
All six teams will be in action again on Friday morning and could still qualify for the quarter-finals.
Find out more about the London 2012 Goalball competition