The Dominican fighter was simply dazzled by the sharp, accurate shots of the 24-year-old Ukrainian Light Weight, who turned a 9-1 advantage at the end of the second into a comfortable 15-3 victory at the end of three rounds.
Lomachenko is making his Olympic Games debut at Light Weight having won the Feather Weight title at Beijing 2008, where he accumulated 58 points in his five bouts and conceded only 13, also winning the Val Barker Trophy for the best boxer of the tournament.
Lomachenko, also a two-time world champion, will next face Puerto Rican teenager Felix Verdejo Sanchez, who beat Tunisia's Ahmed Mejri 16-7, with at least a bronze medal guaranteed for the winner.
Cuba's fourth seed Yasnier Toledo Lopez did not have it all his own way against China's world number nine Lui Qiang, but produced the sharper work to take the verdict 14-10.
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