Wu cemented her place as one of the greatest female divers of all time as she also drew level with former synchro partner Guo Jingjing, who she teamed up with to win the past two Olympic crowns, with a record six medals at the Games.
The 26-year-old could surpass that mark next week, when she and He go head-to-head in the Individual 3m Springboard.
On Day 2 they were comfortable winners, leading after all five rounds to finish with a gap of 24.30 from nearest rivals Abigail Johnston and Kelci Bryant from USA.
Canada's Emilie Heymans and Jennifer Abel took bronze to ensure Heymans became the first diver to win a medal at four consecutive Olympics.
Up to today it is already a miracle what I have achievedWu Minxia
Home duo Becky Gallantree and Alicia Blagg of Great Britain had to be content with seventh place in the eight-team final as errors cost them after being fourth after two rounds.
Wu, whose early career was blighted by injury, could not hide her delight.
'Up to today it is already a miracle what I have achieved,' she said. 'In fact I should call it a marvellous miracle because of what I have overcome.'
Wu has also had to contend with living in the shadow of her now-retired former partner Guo and, while she has now almost certainly etched her own name in history, she played down the significance of any comparisons.
'I've never thought about it. Every person is different. I know my ability and capacity and I have always tried to train as hard as I can every time,' she said.
'I do not want to be compared to anybody. I just want to walk my own path.'