In a meeting of the two remaining winless teams in Group A, Croatia made light work of the African champions, breaking clear late in the first quarter and opening up a double-digit lead before half-time.
They pushed the advantage to 20 early in the fourth quarter to give themselves hope of progressing to the quarter-finals if they can win their final group game against Turkey on Sunday evening.
Ana Lelas led Croatia with 23 points and Sandra Mandir added 18.
Angola did their best to make a fight of it early, tying it 11-11 on Astrida Vicente's jump-shot in the first and then coming from 20-11 down to get within 22-18 late in the first on Angela Cardoso's basket.
But Croatia responded to go 28-18 clear early in the first and Angola's challenge faded as Antonija Misura made it 41-29 to Croatia shortly before half-time.
Luisa Tomas had 14 points and Nadir Manuel 12 for Angola.