Opened by Olympic athlete Denise Lewis OBE, the state-of-the-art centre has £4.8 million of equipment donated by global Olympic Games sponsor GE.
The investment creates a lasting legacy for east London, helping to address a major local issue - infant mortality.
Nancy Hallett, Homerton Hospital Chief Executive, said: 'Homerton is very proud of its great service for mums, dads and babies. And this wonderful gesture from GE will help us deliver even better quality care.
'The new hi-tech facilities will help all the babies born at Homerton, especially those who need special care – who knows, maybe one of them will be a medal winner in years to come and fulfil that Olympic legacy.'